Welcome to Yale University's Thanksgiving festivities! Join us for a variety of events, blending tradition and community spirit for everyone. 

Thanksgiving Parade and Campus Potluck（百家餐）

Time: Thanksgiving Day, 10:30 AM - 1:30 PM

Location: Yale Old Campus

Activities: Immerse yourself in the vibrant Thanksgiving parade featuring spirited floats, the Yale marching band, and talented performers. Following the parade, join the campus potluck on Old Campus. Contribute a dish to share and connect with fellow Yale students. This cherished tradition is an excellent opportunity to experience the warmth of the Yale community. 

Thanksgiving Arts & Crafts Showcase

Time: Thanksgiving Morning, 9:00 AM

Location: Yale Art Gallery

Activities: Discover a diverse array of arts and crafts meticulously crafted by Yale's talented artists. Find unique, handmade gifts for the upcoming holiday season and enjoy live performances and local food vendors. Kick-start your holiday shopping while supporting the artistic talents thriving within the Y ale community. 

Turkey Dash 5K Run

Time: The Weekend Before Thanksgiving, 9:30 AM

Location: Yale Bowl

Activities: Begin your Thanksgiving weekend with a spirited 5K run or walk around the picturesque Yale Bowl. Open to all fitness levels, participants are encouraged to bring extra goods to give them to local charities, promoting wellness and community support. 

Gobble 'n' Games Family Fest

Time: The Saturday Before Thanksgiving, 2:00 PM - 6:00 PM

Location: Beinecke Plaza

Activities: Bring your family for an afternoon of joy and games at Beinecke Plaza. Enjoy sack races（ 袋鼠跳）, face painting, pumpkin decorating, and a pie-eating contest. Local food trucks will be on-site to keep you fueled. This family-friendly event is a delightful way to usher in the holiday season with laughter and connection. 

Plastic, which is now common, contains endocrine-disrupting chemicals, or EDCs (内分泌干扰物), that has been linked to increased risk of many chronic diseases. Parental exposure to EDCs, for example, has been shown to cause metabolic (新陈代谢的) disorders, including obesity and diabetes, in the later generations.

Led by Changcheng Zhou, a professor of biomedical sciences in the School of Medicine at the University of California, the researchers investigated the impact of fathers' exposure to a phthalate called dicyclohexyl phthalate, or DCHP (邻苯二甲酸二环己酯), on the metabolic health of first generation (F1) and second generation (F2) in mice. Phthalates are chemicals used to make plastic more durable.

The researchers found that fathers' DCHP exposure for four weeks led to high insulin (胰岛素) resistance and impaired insulin signaling in F1. The same effect, but weaker, was seen in F2.

"We found fathers' exposure to EDCs may have intergenerational and transgenerational detrimental effects on the metabolic health of their later generations," Zhou said. "To the best of our knowledge, our study is the first to demonstrate this."

In the case of fathers' exposure in the study, intergenerational effects are changes that occur due to direct exposure to a stressor, such as exposure to DCHP of fathers (FO generation) and his Fl generation. Transgenerational effects are changes passed down to later generations that are not directly exposed to the stressor (for example, F2 generation).

"This suggests that fathers' DCHP exposure can lead to sex-specific transgenerational effects on the metabolic health of their later generations," Zhou said.

Zhou stressed that the impact of exposure to DCHP on human health is not well understood, even though DCHP is widely used in a variety of plastic products and has been detected in food, water, and indoor particulate matter.

"It's best to minimize our use of plastic products," Zhou said. "This can also help reduce plastic pollution, one of our most pressing environmental issues."

The American actor Bruce Willis has been diagnosed with frontotempora1 dementia（痴 呆）, "a cruel disease", his family said in1 a statement posted on Thursday to the website of the Association for Frontotemporal Degeneration （AFTD）. Last year, Willis was originally diagnosed with aphasia, a comprehension and communication disorder. His family said at the time that he was "stepping away" from his acting career as a result. "Since we announced Bruce's diagnosis of aphasia in spring 2022, Bruce's condition has progressed and we now have a more specific diagnosis: frontotemporal dementia （known as FTD）, " continued the statement. "Challenges with communication" are one of the symptoms Willis faces with FTD, which is the most common form of dementia in people under 60-with most FTD cases occurring between the ages of 45 and 64, according to the AFTD. The disease is likely more common than statistics suggest, as it is lesser known and can take years to receive a formal diagnosis.

FTD is a degenerative （变性的, 退化的） brain disorder. Symptoms may include uncharacteristic personality changes and unexplained struggles with decision-making, speaking or language comprehension are among the most common presenting symptoms. 

While there is currently neither a cure nor treatments available for the condition, the Willis family writes that they hope to help change this. 

"As Bruce's condition advances, we hope that any media attention can be focused on shining a light on this disease that needs far more awareness and research, " his family said, adding that Willis has always believed in using his voice to raise awareness and help others, both in and out of the public eye. 

"Bruce has always found joy in life—and has helped everyone he knows to do the same, " the statement concluded. "Your continued compassion, understanding, and respect will enable us to help Bruce live as full a life as possible. "